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. 2021 Jan 26;21:37. doi: 10.1186/s12876-021-01613-y

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — Effects of butyric acid on spontaneous contractions of mouse proximal colon in control and IBS model groups. Effects of butyric acid in concentrations of 0.5, 1, 5, 10 and 30 mM on tonic tension (a), amplitude (b) and frequency (c) of contractions of mouse colon segment of the control group (black circle) and in the IBS model group (white circle). d Original recordings of spontaneous contractions of proximal colon during butyric acid (10 mM) application in control and IBS model groups. *p < 0.05 compared to the initial value; # p < 0.05 compared to the effects of butyric acid in control.