Table 1.
Abdominal withdrawal reflex scores for colon distention of mice from IBS model and control groups
| Group | n | Balloon volume, ml | ||||
|---|---|---|---|---|---|---|
| 0.1 | 0.25 | 0.35 | 0.5 | 0.65 | ||
| AWR score | ||||||
| Control | 20 | 0.37 ± 0.09 | 0.83 ± 0.19 | 1.83 ± 0.18 | 2.9 ± 0.14 | 3.63 ± 0.11 |
| IBS model | 15 | 0.53 ± 0.09 | 1.21 ± 0.11 | 2.56 ± 0.22* | 3.38 ± 0.18* | 3.82 ± 0.07 |
AWR scale: 0, no behavioral response; 1, brief movement of the head, followed by immobility; 2, contraction of abdominal muscles; 3, lifting the abdomen, and 4, body flexion and pelvic lift [25]
*p < 0.05 compared with the control group