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. 2021 Jan 26;21:37. doi: 10.1186/s12876-021-01613-y

Table 2.

Contractile activity of mouse proximal colon during acute SCFAs application in the control group

Concentration of SCFAs (mM) Tonic tension (g) Amplitude (g) Frequency (min−1)
Sodium acetate
 Initial value 0.781 ± 0.011 0.735 ± 0.037 2.5 ± 0.126
 0.5 0.748 ± 0.012 0.677 ± 0.033 2.269 ± 0.116
 1 0.704 ± 0.011* 0.584 ± 0.029* 1.965 ± 0.123*
 5 0.681 ± 0.011* 0.489 ± 0.031* 1.86 ± 0.129*
 10 0.659 ± 0.011* 0.423 ± 0.028* 1.368 ± 0.101*
 30 0.621 ± 0.01* 0.378 ± 0.033* 0.565 ± 0.091*
Sodium propionate
 Initial value 0.84 ± 0.014 0.701 ± 0.028 2.14 ± 0.111
 0.5 0.793 ± 0.013 0.662 ± 0.03 2.003 ± 0.132
 1 0.771 ± 0.013* 0.631 ± 0.027 1.649 ± 0.095
 5 0.73 ± 0.014* 0.613 ± 0.028* 1.218 ± 0.094*
 10 0.695 ± 0.014* 0.547 ± 0.025* 0.805 ± 0.085*
 30 0.591 ± 0.007* 0.497 ± 0.014* 0.308 ± 0.081*
Butyric acid
 Initial value 0.861 ± 0.008 1.097 ± 0.073 2.275 ± 0.091
 0.5 0.815 ± 0.015 1.024 ± 0.077 1.537 ± 0.138
 1 0.787 ± 0.015* 0.705 ± 0.037* 0.613 ± 0.044*
 5 0.749 ± 0.015* 0.289 ± 0.02* 0.15 ± 0.032*
 10 0.682 ± 0.02* 0.152 ± 0.009* 0.061 ± 0.025*
 30 0.614 ± 0.026* 0.09 ± 0.006* 0.02 ± 0.01*

*p < 0.05 compared to the initial value