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Precocious centriole disengagement results in an increase in the number of centrioles. HeLa-GFP-centrin1 (green) cells were treated with siCep57 and siCep57L1. 25 × 1.2–µm z-stacks were acquired every 10 min at 40× magnification. Image frames shown are maximum-intensity projections at each time point.
