. 2021 Jan 26;18:6. doi: 10.1186/s12014-021-09313-1

Table 2.

Full list of the 29 proteins whose expression patterns change consistently when comparing pre-eclamptic versus control serum/plasma samples

Accesion^a	Gene name^a	Protein name^a	PE > C^b,d	PE < C^c,d
P00740	F9	Coagulation factor IX	[68]	[69, 70]
P00751	CFB	Complement factor B	[71]	[48, 70, 72]
P01009	SERPINA1	Alpha-1-antitrypsin	[48, 73–75]	[71]
P01023	A2M	Alpha-2-macroglobulin		[68, 71, 74, 76, 77]
P02649	APOE	Apolipoprotein E	[74, 75, 78]	[76]
P02679	FGG	Fibrinogen gamma chain	[68, 74, 78, 79]
P02741	CRP	C-reactive protein	[68, 69, 75, 76]	[80]
P02746	C1QB	Complement C1q subcomponent subunit B	[76]	[68, 69, 72]
P02751	FN1	Fibronectin	[69–71, 74, 75, 79, 81]	[77]
P02760	AMBP	Protein AMBP	[73–76]	[75]
P02766	TTR	Transthyretin		[14, 74, 81, 82]
P02787	TF	Serotransferrin	[48, 69, 78, 79]
P04114	APOB	Apolipoprotein B-100	[77]	[69, 74, 81]
P04196	HRG	Histidine-rich glycoprotein	[68, 69, 75, 82]	[72]
P05155	SERPING1	Plasma protease C1 inhibitor	[71]	[69, 70, 77]
P08514	ITGA2B	Integrin alpha-IIb	[70, 83]
P08697	SERPINF2	Alpha-2-antiplasmin	[84]	[69, 70, 76]
P09237	MMP7	Matrilysin	[70, 83]
P0C0L5	C4B	Complement C4-B		[68, 77, 81, 83]
P10909	CLU	Clusterin	[68, 73–75, 77–79, 81, 85, 86]	[76]
P11464	PSG1	Pregnancy-specific B-1 glycoprotein 1	[77]	[69, 75, 76, 84]
P17813	ENG	Endoglin	[69, 77, 80, 87, 88]
P20742	PZP	Pregnancy zone protein	[68, 69]	[69, 74, 75]
P22352	GPX3	Glutathione peroxidase 3	[89]	[74–76]
P36955	SERPINF1	Pigment epithelium-derived factor	[71, 72, 74, 81]	[76]
P49763	PGF	Placenta growth factor		[70, 83, 87]
Q14624	ITIH4	Inter-alpha-trypsin inhibitor heavy chain H4	[68, 75, 76]	[72]
Q15485	FCN2	Ficolin-2		[70, 80, 90]
Q16610	ECM1	Extracellular matrix protein 1	[87]	[69, 76, 77]

Reference 69 reports two independent data for F9, C1QB, FN1, TF, APOB, HRG, SERPING1, SERPINF2, PSG1, ENG, PZP and ECM1 and four independent data for CRP; reference 70 reports two independent data for FCN2, CFB, MMP7 and PGF and three independent data for ITGA2B; reference 83 reports two independent data for MMP7.

^aAccording to UniprotKB

^bPE > C: expression levels have been described to be higher in pre-eclampsia versus control samples

^cPE < C: expression levels have been described to be lower in pre-eclampsia versus control samples

^dNumbers correspond to bibliographic references