Table 1.
Details of Expression Datasets taken from GEO for the study.
| Disease Type | Disease/Condition | GSE ID | Platform | Tissue | Experimental Design | Data Processing |
|---|---|---|---|---|---|---|
| Chronic | Asthma | GSE64913 | GPL570 [HG-U133_Plus_2] Affymetrix | Epithelial brushings from central and peripheral airways | 42 healthy volunteer, 28 asthmatic patients | Preprocessed: Normalization and log2 transformation by GCRMA method |
| Chronic Obstructive Pulmonary Disorder | GSE112811 | GPL570 [HG-U133_Plus_2] Affymetrix | Blood | 20 COPD patients, 22 healthy volunteers before administration of LPS or saline | Preprocessed: Normalization and log2 transformation by RMA | |
| Cardiovascular | GSE109048 | GPL17586 [HTA-2_0] Affymetrix | Blood platelets | 19 Healthy donors, 19 CAD patients, 19 AMI patients | Preprocessed: SST-RMA normalization and log2 transformation | |
| Hypertension | GSE113439 | GPL6244 [HuGene-1_0-st] Affymetrix | Lung | 15 patients with Pulmonary Arterial Hypertension and 11 normal controls | Preprocessed: Normalization and log2 transformation by RMA | |
| Non-Alcoholic Fatty Liver Disease | GSE49541 | GPL570 [HG-U133_Plus_2] Affymetrix | Liver | 72 patients with NAFLD | Preprocessed: Normalization and log2 transformation by GCRMA method | |
| GSE107037 | GPL570 [HG-U133_Plus_2] Affymetrix | Liver | 33 healthy liver donors | Preprocessed: Normalization and log2 transformation by RMA | ||
| Atherosclerosis | GSE28829 | GPL570 [HG-U133_Plus_2] Affymetrix | Carotid artery | Samples from atherosclerotic carotid artery segments of 29 patients | Preprocessed: Normalization and log2 transformation by RMA | |
| Type 2 Diabetes | GSE15653 | GPL96 [HG-U133A] Affymetrix | Liver | 4 type 2 diabetes and 5 control subjects | Preprocessed: MAS5.0 signal intensity. | |
| GSE25462 | GPL570 [HG-U133_Plus_2] Affymetrix | Muscle | 10 subjects with type 2 diabetes and 15 healthy subjects | Preprocessed: MAS5.0 signal intensity. | ||
| GSE38642 | GPL6244 [HuGene-1_0 -st] Affymetrix | Pancreas | 54 non-diabetic and 9 diabetic cadavers | Preprocessed: Normalization and log2 transformation by RMA | ||
| GSE27949 | GPL570 [HG-U133_Plus_2] Affymetrix | Adipose | 12 Normal and 11 T2D subjects | Preprocessed: Normalization and log2 transformation by RMA | ||
| Polycystic Ovary Syndrome | GSE124226 | GPL570 [HG-U133_Plus_2] Affymetrix | Adipose | 4 PCOS women and 4 control subjects | Preprocessed: Normalization and log2 transformation by RMA | |
| Multiple Sclerosis | GSE21942 | GPL570 [HG-U133_Plus_2] Affymetrix | PBMCs | 12 MS patients and 15 controls | Preprocessed: Normalization GCRMA method | |
| Psoriasis | GSE78097 | GPL570 [HG-U133_Plus_2] Affymetrix | Skin | 6 normal skin tissues and 27 psoriatic skin lesions | Preprocessed: Normalization GCRMA method | |
| Cancer | Blood Cancer (Leukemia) | GSE51082 | GPL96 [HG-U133A] Affymetrix | Bone Marrow | 37 AML, 41, BCLL1, 22 CML, 10 MDS, 17 B-ALL, 12 T-ALL | Preprocessed: Normalization and log2 transformation by RMA |
| GSE9476 | GPL96 [HG-U133A] Affymetrix | Bone Marrow | 38 healthy donors | Preprocessed: Normalization and log2 transformation by RMA | ||
| Breast Cancer | GSE65194 | GPL570 [HG-U133_Plus_2] Affymetrix | Breast sample | 11 control breast sample, 98 breast cancer samples, 55 TNBC samples | Preprocessed: Normalization and log2 transformation by GCRMA method | |
| Cervical Cancer | GSE63514 | GPL570 [HG-U133_Plus_2] Affymetrix | Cervix | 24 normal and 28 cancer specimens | Preprocessed: Normalization and log2 transformation by GCRMA method | |
| Multiple Myeloma | GSE85837 | GPL10558 Illumina HumanHT-12 V4.0 | Bone Marrow | 9 control and 9 multiple myeloma patients with bone lesion | Preprocessed: Robust spline normalization and log2 transformation by lumi R package | |
| Lung Cancer | GSE136043 | GPL13497 Agilent-026652 | Lung | 5 lung cancer tissue and 5 lung non-tumor tissues | Preprocessed: Normalization by Agilent Feature Extraction Software | |
| Lung adenocarcinoma (Non-small cell lung cancer) | GSE118370 | GPL570 [HG-U133_Plus_2] Affymetrix | Lung | 6 invasive lung adenocarcinoma tissues and 6 normal lung tissues | Preprocessed: Normalization and log2 transformation by MAS5.0 algorithm | |
| Liver Cancer | GSE88839 | GPL570 [HG-U133_Plus_2] Affymetrix | Liver | 35 HCA liver tumours and 3 normal liver samples | Preprocessed: Normalization by RMA | |
| Pancreatic Ductal Adenocarcinoma | GSE101448 | GPL10558 Illumina HumanHT-12 V4.0 | Pancreas | 18 with pancreatic tumor and 13 non-tumor pancreatic tissue samples | Preprocessed: Normalization and log2 transformation by Illumina's BeadStudio Data Analysis Software | |
| Infectious | AIDS | GSE73968 | GPL6244 [HuGene-1_0-st] Affymetrix | T Cells | 9 healthy control and 6 HIV positive patients | Preprocessed: Normalization and log2 transformation by RMA |
| Tuberculosis | GSE139825 | GPL10558 Illumina HumanHT-12 V4.0 | Alveolar Macrophages | Alveolar Macrophages from 5 TB patients and 5 control subjects | Preprocessed: Normalization and log2 transformation by lumi R package | |
| Malaria | GSE119150 | GPL15207 [Prime View] Affymetrix | Blood | 6 falciparum malaria and 6 normal subjects | Preprocessed: Normalization and log2 transformation by RMA | |
| Acute | Acute Kidney Injury | GSE30718 | GPL570 [HG-U133_Plus_2] Affymetrix | Kidney | 28 transplants with AKI to 11 pristine protocol biopsies of stable transplants | Preprocessed: Normalization and log2 transformation by RMA |
| COVID-19 | GSE150316 | GPL18573 | Lung | 16 lung samples with COV2 positive and 5 control lung samples | Preprocessed: DEseq2 normalized |