TABLE 1.
Clinical characteristics of the patients with Mycobacterium abscessus respiratory isolates
| Patients n | 371 |
| Age years | 67 (55–77) |
| Men | 189 (50.9) |
| NTM-pulmonary disease | 260 (70.1) |
| Nodular-bronchiectatic type | 137 (36.9) |
| Fibro-cavitary type | 14 (3.8) |
| Mixed or other type | 109 (29.3) |
| Underlying lung diseases | 183 (49.3) |
| Bronchiectasis | 131 (35.3) |
| Chronic obstructive pulmonary disease | 57 (15.4) |
| Remote history of pulmonary tuberculosis | 58 (15.6) |
| Interstitial lung disease | 3 (0.8) |
| Pneumoconioses | 1 (0.3) |
| Diabetes mellitus | 72 (19.4) |
| Congestive heart failure | 39 (10.5) |
| Chronic kidney disease stage IV–V | 26 (7.0) |
| Chronic hepatitis B | 28 (7.5) |
| Chronic hepatitis C | 11 (3.0) |
| Autoimmune disease | 18 (4.9) |
| Anti-interferon-γ autoantibodies | 9 (2.4) |
| Anti-GM-CSF autoantibodies | 1 (0.3) |
| Gastro-oesophageal reflux disease | 43 (11.6) |
| Human immunodeficiency virus infection | 1 (0.3) |
| Haematological/bone marrow transplantation | 5 (1.3) |
| Solid organ transplantation | 3 (0.8) |
| Thyroid disease | 22 (5.9) |
| Neurological disease | 76 (20.5) |
| Malignancy | 89 (24.0) |
| Head and neck cancer | 22 (5.9) |
| Upper gastrointestinal cancer | 16 (4.4) |
| Lung cancer | 13 (3.5) |
| Renal, bladder and prostate cancer | 11 (3.0) |
| Colorectal cancer | 9 (2.4) |
| Breast cancer | 9 (2.4) |
| Haematological | 5 (1.3) |
| Neuroendocrine | 3 (0.8) |
| Other | 4 (1.1) |
| Deaths during follow-up | 113 (30.5) |
| In-hospital deaths | 66 (17.8) |
| Cause of death: sepsis (including pneumonia) | 34 (9.2) |
| Cause of death: pneumonia | 30 (8.1) |
| Cause of death: NTM-PD | 5 (1.3) |
| Cause of death: cancer | 6 (1.6) |
| Cause of death: haemorrhage | 4 (1.1) |
| Duration of follow-up years | 2.8±8.7 |
Data are presented as median (interquartile range), n (%) or mean±sd, unless otherwise stated. NTM: nontuberculous mycobacteria; GM-CSF: granulocyte–macrophage colony-stimulating factor.