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Hypomethylating Agent Therapy and Response.
| CMML (n=12) | MDS (n=27) | p | |
|---|---|---|---|
| Hypomethylating Agent | |||
| Single-Agent Azacitidine | 4 (33.3%) | 13 (48.1%) | 0.091 |
| Single-Agent Decitabine | 5 (41.7%) | 3 (11.1%) | |
| Azacitidine in Combination | 2 (16.7%) | 10 (37.0%) | |
| Decitabine in Combination | 1 (6.3%) | 0 | |
| Other | 0 | 1 (3.7%) | |
| Response | |||
| Complete Remission (CR) | 3 (25.0%) | 11 (40.7%) | 0.12 |
| Marrow CR (mCR) | 2 (16.7%) | 0 | |
| Hematological Improvement (HI) | 1 (6.3%) | 5 (18.5%) | |
| Overall Response Rate (ORR) | 6 (50.0%) | 16 (59.3%) | 0.73 |
