Table 2.
Complications during hospitalization of SARS-CoV-2 patients.
| Variable | Total (N = 175) n (%) | AI/IMID (n = 58) | Non-AI/IMID (n = 117) | P value |
|---|---|---|---|---|
| Severe SARS-CoV-2a | 64 (36.6) | 12 (20.7) | 52 (44.4) | 0.002 |
| ARDS | 59 (33.7) | 7 (12.1) | 52 (44.4) | 0.000 |
| ICU admission | 50 (28.6) | 8 (13.8) | 42 (35.9) | 0.003 |
| Invasive mechanical ventilation | 29 (16.6) | 4 (6.7) | 25 (21.3) | 0.008 |
| Non-invasive ventilation | 10 (5.7) | 4 (6.9) | 6 (5.1) | 0.635 |
| High-flow oxygen | 29 (16.6) | 2 (3.4) | 27 (23.1) | 0.119 |
| Prone ventilation | 9 (5.1) | 0 (0.0) | 9 (7.7) | 0.003 |
| Organizing Pneumonia | 32 (18.3) | 6 (10.3) | 26 (22.2) | 0.056 |
| ECMO | 2 (1.1) | 1 (1.7) | 1 (0.9) | 0.317 |
| Vasoactive/inotropic drugs | 11 (6.3) | 4 (6.9) | 7 (6.0) | 0.080 |
| Hospital-acquired infection | 21 (12.0) | 3 (5.2) | 18 (15.4) | 0.050 |
| Acute kidney injury Without hemodialysis/hemofiltration With hemodialysis/hemofiltration |
17 (9.7) 4 (2.3) |
3 (5.2) 1 (1.7) |
14 (12.0) 3 (2.6) |
0.153 0.726 |
| Thromboembolic eventb | 13 (7.4) | 2 (3.4) | 11 (9.4) | 0.157 |
| Cardiovascular eventc | 11 (6.3) | 3 (5.2) | 8 (6.8) | 0.669 |
| Hemorrhagic complications | 8 (4.6) | 3 (5.2) | 5 (4.3) | 0.789 |
| Mortality | 13 (7.4) | 4 (6.9) | 9 (7.7) | 0.850 |
AI/IMID: autoimmune or immune-mediated inflammatory disease; ARDS: Acute Respiratory Distress Syndrome; ECMO: Extracorporeal membrane oxygenation; ICU: Intensive care unit.
a
Defined as: intensive care unit admission, intratracheal intubation, cardiovascular complications (heart failure or myocarditis), thrombosis, kidney failure requiring hemodialysis, and death.
b
Venous thromboembolic disease (either deep vein thrombosis or pulmonary embolism), or arterial thrombosis.
c
Include congestive heart failure, new-onset heart arrhythmias, and acute myocardial infarction.