Table II.
Summary and timings of biochemical and echocardiographic markers in relation to events during MIS-C illness
| Biochemical markers (peak value) | Median (IQR) | Ref. Range |
|---|---|---|
| CRP (mg/L) | 187 (118, 287.5) | 0-4 |
| Ferritin (μg/L) | 631 (354, 1120) | 22-275 |
| Troponin (ng/L) | 38 (8, 118.5) | 0-13 |
| NT-pro BNP (ng/L) | 2613 (1100, 6485) | <100 |
| Echocardiographic measurements (worst value) | ||
| Global longitudinal strain (-%) | 15 (18.35, 12) | >18% |
| Fractional shortening (%) | 29.6 (24.95, 33.7) | 28%-45% |
| Timeline of illness - Events timed from symptom onset: | Days (median, IQR): | |
| Admission to hospital | 5 (3, 5) | |
| Peak CRP | 5 (4, 7) | |
| Peak ferritin | 5 (4, 7) | |
| Peak troponin | 6 (4, 7) | |
| Peak NT-proBNP | 6 (5, 7) | |
| Peak number of negative T-waves in chest leads (ECG) | 6 (5, 7) | |
| Worst global longitudinal strain (echocardiogram) | 6 (5, 8) | |
| Discharge from PICU (those admitted) | 9 (6.5, 10.5) | |
| Discharge from hospital | 11 (10, 14) | |
| Follow-up length | 58 (44, 67) | |
CRP, C-reactive protein; Nt-pro BNP, N-terminal pro-brain-natriuretic peptide.