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. 2020 Oct 17;133:116081. doi: 10.1016/j.trac.2020.116081

Table 1.

Summary table on the various literature electrochemical methods based on their applications, LOD and analysis time.

Detection Approach Electrochemical Platforms Target Analyte Detected LOD Analysis
Time
References
Detection of coronavirus-related proteins Metal-Oxide-Semiconductor FET (MOSFET) SARS-CoV
N protein
Sub-nanomolar concentrations 10 min [30]
Carbon nanotube FET (CNTFET) SARS-CoV
N protein
5 nM 10 min [33]
High-Electron-Mobility Transistor FET (HEMT) SARS-CoV
N protein
0.003 nM (0.4 pg) [34]
Graphene-based FET (GFET) SARS-CoV-2
S protein
2.42 × 102 copies/ml (clinical samples) [36]
Array of AuNPs-modified carbon electrodes MERS-CoV,
OC43
0.4 pg/mL (OC43);
1.0 pg/mL (MERS-CoV)
[37]
Eight-channel AuSPEs SARS-CoV-2
S protein
1 fg/mL 3 min [35]
Detection of viral DNA Gold films SARS-CoV
30-mer sequence
6 pmol/L [42]
Polylysine SARS-CoV 5 pmol/L [44]
modified SPCEs 30-mer sequence 8 pmol/L [45]
Au nanostructured SPCEs SARS-CoV
30-mer sequence
2.5 pmol/L [43]
Au/Au/Au electrode system SARS-CoV up to 400,000 copies [46]
Glassy carbon SARS-CoV
30-mer sequence
5.0 pg/μL [41]
AuSPEs modified with CNTs SARS-CoV
15-/30-mer sequence
800 nM [47]
Gold screen-printed electrodes (AuSPEs) Coronavirus
Aviair (174 bp)
5 ng/mL 30 min [49]
AuNPs electrodeposited on Ti surface SARS-CoV-2 [50]
Detection of PCR Products NanoChip 400 system
Gold
OC43, 229E and HKU1 760 ng/μL (OC43);
128 ng/μL (229E)
[54]
SARS-CoV-2 1 × 105 copies/mL Under 2 h [51]
Detection of ROS Steel tips modified with MWCNTs SARS-CoV-2
ROS level
30 s [59]