Table 1.
Summary table on the various literature electrochemical methods based on their applications, LOD and analysis time.
| Detection Approach | Electrochemical Platforms | Target Analyte Detected | LOD | Analysis Time |
References |
|---|---|---|---|---|---|
| Detection of coronavirus-related proteins | Metal-Oxide-Semiconductor FET (MOSFET) | SARS-CoV N protein |
Sub-nanomolar concentrations | 10 min | [30] |
| Carbon nanotube FET (CNTFET) | SARS-CoV N protein |
5 nM | 10 min | [33] | |
| High-Electron-Mobility Transistor FET (HEMT) | SARS-CoV N protein |
0.003 nM (0.4 pg) | – | [34] | |
| Graphene-based FET (GFET) | SARS-CoV-2 S protein |
2.42 × 102 copies/ml (clinical samples) | – | [36] | |
| Array of AuNPs-modified carbon electrodes | MERS-CoV, OC43 |
0.4 pg/mL (OC43); 1.0 pg/mL (MERS-CoV) |
– | [37] | |
| Eight-channel AuSPEs | SARS-CoV-2 S protein |
1 fg/mL | 3 min | [35] | |
| Detection of viral DNA | Gold films | SARS-CoV 30-mer sequence |
6 pmol/L | – | [42] |
| Polylysine | SARS-CoV | 5 pmol/L | – | [44] | |
| modified SPCEs | 30-mer sequence | 8 pmol/L | – | [45] | |
| Au nanostructured SPCEs | SARS-CoV 30-mer sequence |
2.5 pmol/L | – | [43] | |
| Au/Au/Au electrode system | SARS-CoV | up to 400,000 copies | – | [46] | |
| Glassy carbon | SARS-CoV 30-mer sequence |
5.0 pg/μL | – | [41] | |
| AuSPEs modified with CNTs | SARS-CoV 15-/30-mer sequence |
800 nM | – | [47] | |
| Gold screen-printed electrodes (AuSPEs) | Coronavirus Aviair (174 bp) |
5 ng/mL | 30 min | [49] | |
| AuNPs electrodeposited on Ti surface | SARS-CoV-2 | – | – | [50] | |
| Detection of PCR Products | NanoChip 400 system Gold |
OC43, 229E and HKU1 | 760 ng/μL (OC43); 128 ng/μL (229E) |
– | [54] |
| SARS-CoV-2 | 1 × 105 copies/mL | Under 2 h | [51] | ||
| Detection of ROS | Steel tips modified with MWCNTs | SARS-CoV-2 ROS level |
– | 30 s | [59] |