Skip to main content
. 2020 Oct 17;133:116081. doi: 10.1016/j.trac.2020.116081

Table 2.

Summary table on the present diagnostics used for SARS-CoV-2 on their limits of detection (LOD) and analysis time.

Detection Approach Diagnostic Platforms Target Analyte Detected LOD Analysis Time References
Nucleic acid amplification qRT-PCR SARS-CoV-2 E and RdRp genes 3.9 copies/reaction (E gene);
3.6 copies/reaction (RdRp gene)
2–4 h [61]
RT-LAMP with colorimetric detection SARS-CoV-2 100 copies/reaction 30–60 min [62]
Detection of viral antibodies and antigens Capture ELISA immunoassay anti-SARS-CoV-2 IgG and IgM 2.384a (IgG);
2.187a (IgM)
2.5 h [63]
ELISA immunoassay SARS-CoV-2 antigens (N and S proteins) 100 pg/mL 3–5 h [64]
a

Fold change over average reading of negative controls.