Table 1.

SLC Transporter Families That Move Buffer Species

SLC Family	Family Name: Transported Buffer Substrate
SLC1	Glutamate and neutral amino acids113: H+, glutamate−, aspartate−, glutamine+, asparagine+
SLC4	Bicarbonate transporters39: HCO3−, CO32− (borate)
SLC5	Na+ glucose cotransporters114: SLC5 and SLC12: monocarboxylates, short-chain fatty acids, lactate−, pyruvate−, acetoacetate−
SLC9	Na+/H+ exchangers115: H+, NH4+
SLC11	H+-coupled metal ion transporters116: H+
SLC12	Electroneutral cation-coupled Cl cotransporters117: NH4+
SLC13	Na+ sulfate/carboxylate cotransporters118: dicarboxylates (eg, succinate, citrate)
SLC15	H+-coupled oligopeptide cotransporters119: H+, charged peptides, β-lactam antibiotics
SLC16	Monocarboxylate transporters: H+, monocarboxylates
SLC20/SLC34	Na+ phosphate cotransporters120: H2PO4−, HPO42−
SLC21	Organic anion transporters121
SLC22	Organic cation/anion/zwitterion transporters122
SLC26	Multifunctional anion exchangers31: HCO3−, formate−, SO42−
SLC36	H+-coupled amino acid transporters123: H+
SLC38	System A and system N Na+-coupled neutral amino acid transporter family123: H+, charged amino acids
SLC42	Rh ammonium transporters43: NH3, NH4+
SLC46	Folate transporters124: H+
SLC47	Multidrug and toxin extrusion family125: tetraethylammonium

Note. Current SLC tables are available at http://slc.bioparadigms.org.