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. 2020 Nov 11;56(11):758–759. doi: 10.1016/j.arbr.2020.10.008

Table 1.

Sensitivity, specificity, PPV, LR+, LR− and NPV with 95% confidence interval for highest levels of D-dimer (mcg/L) at different cut-off points for prediction pulmonary embolism in patients with COVID-19 during hospitalization.

D-dimer cut-off Sensitivity LR+ PPV Specificity LR− NPV
2000 1.00 (1.00–1.00) 1.79 (1.26–2.53) 0.60 (0.44–0.76) 0.44 (0.25–0.63) 0.00 1.00 (1.00–1.00)
3000 0.90 (0.77–1.00) 1.88 (1.22–2.89) 0.60 (0.42–0.78) 0.52 (0.32–0.72) 0.19 (0.05–0.75) 0.87 (0.69–1.00)
5000 0.76 (0.58–0.94) 1.90 (1.11–3.26) 0.62 (0.43–0.80) 0.60 (0.41–0.79) 0.40 (0.17–0.91) 0.75 (0.56–0.94)
10,000 0.57 (0.36–0.78) 2.38 (1.08–5.25) 0.67 (0.45–0.88) 0.76 (0.59–0.93) 0.56 (0.32–0.99) 0.68 (0.51–0.85)
15,000 0.48 (0.26–0.69) 2.98 (1.09–8.18) 0.71 (0.48–0.95) 0.84 (0.70–0.98) 0.62 (0.39–1.00) 0.66 (0.49–0.82)
30,000 0.26 (0.08–0.44) 3.78 (0.84–17.02) 0.75 (0.45–1.00) 0.93 (0.84–1.00) 0.79 (0.58–1.00) 0.61 (0.47–0.76)

Definition of abbreviations: LR+, positive likelihood ratio; LR−, negative likelihood ratio; PPV, positive predicted value; NPV, negative predicted value.