Table 1.
D-dimer cut-off | Sensitivity | LR+ | PPV | Specificity | LR− | NPV |
---|---|---|---|---|---|---|
2000 | 1.00 (1.00–1.00) | 1.79 (1.26–2.53) | 0.60 (0.44–0.76) | 0.44 (0.25–0.63) | 0.00 | 1.00 (1.00–1.00) |
3000 | 0.90 (0.77–1.00) | 1.88 (1.22–2.89) | 0.60 (0.42–0.78) | 0.52 (0.32–0.72) | 0.19 (0.05–0.75) | 0.87 (0.69–1.00) |
5000 | 0.76 (0.58–0.94) | 1.90 (1.11–3.26) | 0.62 (0.43–0.80) | 0.60 (0.41–0.79) | 0.40 (0.17–0.91) | 0.75 (0.56–0.94) |
10,000 | 0.57 (0.36–0.78) | 2.38 (1.08–5.25) | 0.67 (0.45–0.88) | 0.76 (0.59–0.93) | 0.56 (0.32–0.99) | 0.68 (0.51–0.85) |
15,000 | 0.48 (0.26–0.69) | 2.98 (1.09–8.18) | 0.71 (0.48–0.95) | 0.84 (0.70–0.98) | 0.62 (0.39–1.00) | 0.66 (0.49–0.82) |
30,000 | 0.26 (0.08–0.44) | 3.78 (0.84–17.02) | 0.75 (0.45–1.00) | 0.93 (0.84–1.00) | 0.79 (0.58–1.00) | 0.61 (0.47–0.76) |
Definition of abbreviations: LR+, positive likelihood ratio; LR−, negative likelihood ratio; PPV, positive predicted value; NPV, negative predicted value.