Table 1.
Definition of hypertensiona | |||||||
---|---|---|---|---|---|---|---|
Classification systems | CTCAE 3.0 (2006) (30) |
CTCAE 4.03 (2010) (26) |
JNC-7 (2003) (28)b |
ESH/ESC (2013) (27) |
|||
Systolic | Diastolic | Systolic | Diastolic | Systolic | Diastolic | ||
Grade 1 | Asymptomatic Transient (<24 h) Increase >20 (diastolic) > 150/100 if previously normal | 120–139 | 80–89 | 140–159 | 90–99 | 140–159 | 90–99 |
Grade 2 | Recurrent/persistent (≥24 h) symptomatic increase >20 (diastolic) > 150/100 if previously normal | 140–159 | 90–99 | ≥160 | ≥100 | 160–179 | 100–109 |
Grade 3 | Requiring >1 drug Requiring more intensive therapy than previously | ≥160 | ≥100 | ND | ND | ≥180 | ≥110 |
Grade 4 | Life-threatening consequences | Life-threatening consequences | ND | ND | ND | ND | ND |
Grade 5 | ND | Death | ND | ND | ND | ND | ND |
Abbreviations: CTCAE common terminology criteria for adverse events, JNC joint national committee, ESH European society of hypertension, ESC European society of cardiology, ND not defined
a All numeric blood pressure values are in mm Hg
b The current JNC-8 report (2013) [115] does not classify grades of hypertension