Table 1.
Clinical Characteristics and Hormone Levels in 28 Patients Admitted with Acute COVID-19 Infection
| Age (y) | Sex | Medical background | Severity of disease | Days 1-2 |
Days 3-5 |
Days 8-11 |
|||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Cortisol nmol/L | ACTH ng/L | DHEAS nmol/L | Cortisol nmol/L | ACTH ng/L | DHEAS nmol/L | Cortisol nmol/L | ACTH nmol/L | ||||
| 37 | F | Healthy | A | 181 | 19.1 | 6.45 | 445 | 30.5 | 6.75 | 329 | 16.9 |
| 31 | M | Healthy | B | 386 | 26.1 | 4.26 | 242 | 58.9 | 4.6 | 199 | 50.2 |
| 25 | M | Osteomyelitis of the jaw | B | 106 | 24.7 | 11.3 | 124 | 12.9 | 11.2 | 89.8 | 16.4 |
| 69 | F | HTN, osteoarthritis | B | 97 | 24 | 0.273 | 168 | 15.8 | 0.235 | 180 | 25.4 |
| 52 | M | DM 2, HTN, hypothyroidism | B | 149 | 9.4 | 1.96 | 313 | … | 1.78 | 229 | 5.6 |
| 35 | M | Healthy | A | 98.4 | 20.7 | 6.18 | 334 | 41.6 | 6.45 | 309 | 35.2 |
| 28 | F | Endometriosis | B | 30.6 | 24.2 | 2.36 | 26.7 | 27 | 2.22 | 57.4 | 7.3 |
| 34 | M | DM | A | 202 | 7.8 | 3.44 | 113 | 3.9 | 3.26 | 327 | 3.1 |
| 48 | M | Healthy | A | 96.9 | 17 | … | … | … | … | … | … |
| 46 | F | Healthy | A | 299 | 7.6 | 3.52 | 644 | 8.9 | 3.27 | 238 | 5.8 |
| 30 | F | Healthy | B | 162 | 19.1 | 2.73 | 499 | 32.6 | … | … | … |
| 56 | F | DM, dyslipidemia | B | 324 | 12.7 | 1.78 | … | 4.9 | … | … | … |
| 58 | M | Dyslipidemia | B | 190 | 18.9 | 5.52 | 518 | 39.1 | … | … | … |
| 31 | M | Healthy | A | 416 | 30 | … | … | … | … | 447 | … |
| 48 | M | HTN | B | 232 | 11.7 | 3.94 | 122 | 9.2 | 3.72 | 197 | … |
| 35 | F | HTN | B | 76.3 | 13.6 | 3.28 | 252 | 10.8 | 3.08 | 266 | 19.4 |
| 27 | M | Healthy | B | 133 | 19.9 | 8.65 | 361 | 48.6 | 10.1 | 77.1 | … |
| 49 | M | Healthy | A | 432 | 38.3 | 3.88 | 421 | 40.3 | 4.01 | … | … |
| 42 | F | Healthy | C | 482 | 4.0 | … | … | 1.8 | … | … | … |
| 26 | F | Healthy | A | 36.2 | 11.7 | … | … | … | … | … | … |
| 25 | F | Healthy | C | 37 | 8.4 | 3.1 | 52 | 8.6 | 3.8 | … | … |
| 54 | M | DM 2, HTN, IHD | A | 82 | 11 | 1.4 | 316 | 27 | 1.3 | … | … |
| 45 | F | Healthy | B | 330 | 6.7 | 6.6 | … | … | … | … | … |
| 54 | M | DM, HTN, dyslipidemia | A | 429 | 357 | 3.1 | … | … | 2.7 | … | … |
| 55 | M | Healthy | B | 366 | 17.9 | 2.35 | 380 | 22.6 | 1.8 | 328 | 28.7 |
| 61 | F | Healthy | B | 432 | 5.2 | 1.52 | 469 | 28 | 1.28 | 594 | 8.5 |
| 57 | M | Healthy | B | 291 | 31.9 | … | … | … | 1.84 | … | … |
| 50 | M | DM, HTN, dyslipidemia | A | 587 | 32.4 | 5.31 | 298 | 42.9 | … | … | … |
Abbreviations: ACTH = adrenocorticotropic hormone; COVID-19 = coronavirus disease-2019; DHEAS = dehydroepiandrosterone sulfate; DM 2 = diabetes mellitus type 2; F = female; HTN = hypertension; IHD = ischemic heart disease; M = male.