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. Author manuscript; available in PMC: 2021 Oct 21.
Published in final edited form as: Biomater Sci. 2020 Sep 2;8(20):5516–5537. doi: 10.1039/d0bm01183e

Figure 3.

Figure 3.

Overview of local and systemic approaches for drug delivery. Local approaches consist of hydrogels, scaffolds (implantable and injectable), and microparticles. Systemic approaches consist of nanoparticles (lipid-, polymer-, and natural-based) and drug conjugates (antibody-drug conjugates and polymer-drug conjugates).