Table 1.
Baseline and clinical characteristics of patients admitted to critical care with COVID-19.
| Demographics | Total [n = 143] | No AKI [n = 28,19.6%] | AKI stage 1–2 [n = 15, 10.5%, stage1 = 8, 5.6%, stage 2 = 7, 4.9%) | AKI stage 3 [n = 93, 65.0%] |
|---|---|---|---|---|
| Age (years) | [n = 143] | [n = 28] | [n = 15] | [n = 93] |
| Mean (SD) | 56.3 (11.9) | 49.5 (12.2) | 53.3 (14.6) | 59.0 (10.8) |
| Median (IQR) | 57 (50–63) | 50.5 (42.5–60.5) | 57 (41–65) | 59 (52–65) |
| Sex, n (%) | [n = 143] | [n = 28] | [n = 15] | [n = 93] |
| Female | 48 (33.6) | 13 (46.4) | 5 (33.3) | 27 (29.0) |
| Male | 95 (66.4) | 15 (53.6) | 10 (66.7) | 66 (71.0) |
| Ethnicity, n (%) | [n = 141] | [n = 28] | [n = 14] | [n = 92] |
| White | 43 (30.5) | 9 (32.1) | 8 (57.1) | 24 (26.1) |
| Mixed | 0 | 0 | 0 | 0 |
| Asian | 15 (10.6) | 5 (17.9) | 0 | 9 (9.8) |
| Black | 74 (52.5) | 11 (39.3) | 4 (28.6) | 55 (59.8) |
| Other | 9 (6.4) | 3 (10.7) | 2 (14.3) | 4 (4.3) |
| BMI (kg/m2), n (%) | [n = 134] | [n = 27] | [n = 13] | [n = 88] |
| <18.5 | 1 (0.7) | 0 | 0 | 1 (1.1) |
| 18.5–<25 | 38 (28.4) | 9 (33.3) | 2 (15.4) | 26 (29.5) |
| 25–<30 | 46 (34.3) | 11 (40.7) | 4 (30.8) | 28 (31.8) |
| 30–<40 | 39 (29.1) | 6 (22.2) | 5 (38.5) | 27 (30.7) |
| 40+ | 10 (7.5) | 1 (3.7) | 2 (15.4) | 6 (6.8) |
| Comorbidities, n (%) | [n = 143] | [n = 28] | [n = 15] | [n = 93] |
| Hypertension | 78 (54.5) | 8 (28.6) | 8 (53.3) | 59 (63.4) |
| Diabetes Mellitus | 63 (44.1) | 6 (21.4) | 7 (46.7) | 45 (48.4) |
| Coronary Artery Disease | 11 (7.7) | 0 | 3 (20) | 8 (8.6) |
| Chronic Kidney Disease | 23 (16.1) | 1 (3.6) | 2 (13.3) | 13 (14.0) |
| Chronic Kidney Disease, n (%) | [n = 143] | [n = 28] | [n = 15] | [n = 93] |
| Stage 3a | 5 (3.5) | 1 (3.6) | 1 (6.7) | 3 (3.2) |
| Stage 3b | 7 (4.9) | 0 | 1 (6.7) | 6 (6.5) |
| Stage 4 | 4 (2.8) | 0 | 0 | 4 (4.3) |
| Stage 5 - PD/IHD | 5 (3.5) | 0 | 0 | 0 |
| Stage 5 - Transplant | 2 (1.4) | 0 | 0 | 0 |
| Organ support, n (%) | [n = 143] | [n = 28] | [n = 15] | [n = 93] |
| MV at any time | 133 (93.0) | 25 (89.3) | 10 (66.7) | 92 (98.9) |
| ECMO at any timea | 10 (7.0) | 1 (3.6) | 0 | 9 (9.7) |
Abbreviations: AKI, acute kidney injury; SD, standard deviation; IQR, interquartile range; BMI, body mass index; ACEi, angiotensin converting enzyme inhibitor; ARB, angiotensin II receptor blocker; MV, mechanical ventilation; ECMO, extracorporeal membrane oxygenation.
a
Of the 10 patients treated with ECMO, this therapy was provided at our trust in 1 case and the patient was transferred to a regional Severe Respiratory Failure centre in 9 cases.