Skip to main content
. 2020 Oct 8;83(Supple 1):S63–S74. doi: 10.4046/trd.2020.0112

Figure 4.

Figure 4.

The effect of bleomycin (BLE), chronic intermittent hypoxia (CIH), and pirfenidone (PF) on lung inflammation. (A) Bronchoalveolar lavage (BAL) cells were isolated, after which total cell numbers and the numbers of different inflammatory cell types were counted. (B) Activity of the inflammatory enzyme myeloperoxidase (MPO) was measured in total lung homogenates from mice. (C–F) The levels of albumin (C) and the proinflammatory cytokines interleukin (IL)-6 (D), IL-1β (E), and tumor necrosis factor α (TNF-α) (F) in BAL fluid were measured by enzyme-linked immunosorbent assay. The data shown are expressed as the mean±SD. *p<0.05, **p<0.01, ***p<0.001 vs. the CIH+BLE group. †p<0.05, ††p<0.01, †††p<0.001 vs. the normoxia (NOR)+BLE group. ‡p<0.05, ‡‡p<0.01, ‡‡‡p<0.001 vs. the CIH+BLE+PF group. §p<0.05, §§p<0.01, §§§p<0.001 vs. the NOR+BLE+PF group.