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The effects of bleomycin (BLE), chronic intermittent hypoxia (CIH), and pirfenidone (PF) on oxidative stress. (A, B) The levels of malondialdehyde (MDA; as a lipid peroxidation marker) (A) and superoxide dismutase (SOD; as an indicator of oxidative stress) (B) were measured in the total lung homogenates from the mice in each group. NOR: normoxia. The data shown are expressed as the mean±SD. *p<0.05, **p<0.01 vs. the CIH+BLE group.
