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. Author manuscript; available in PMC: 2021 Feb 1.
Published in final edited form as: Gastroenterology. 2019 Nov 9;158(3):679–692.e1. doi: 10.1053/j.gastro.2019.10.038

Figure 6. ZIP4, ZEB1 and integrins regulate pancreatic cancer metastasis and chemoresistance through gemcitabine transporter ENT1.

Figure 6.

After 48 h treatment with gemcitabine, ENT1 expression was determined in (A). AsPC-1 and MIA PaCa-2 cells. (B). MIA-ZIP4 siZEB1 cells. (C). AsPC-shZIP4-ZEB1 cells (transient transfection). (D). MIA-ZIP4 siITGA3 or siITGB1 cells. (E). AsPC-shZIP4 cells with ITGA3 or ITGB1 overexpressed (transient transfection).