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. 2020 Dec 30;16(12):e1007937. doi: 10.1371/journal.pcbi.1007937

Fig 7. Simulations of synaptic excitation and inhibition.

Fig 7

(A) The traces show spikes elicited by a single stimulus on 2 MF, 3 AA, and 12 PFs. The number of synapses that need to the activated simultaneously in order to elicit a spike is shown in the box-and-whiskers plots, which report the effect of stimuli delivered after switch-off of pacemaking with a small negative current. (B) PSTH of responses elicited by a short train (5 impulses @100 Hz) to 20 MF, 20 AA, and 89 PF synapses. Note that the response bursts are followed by a pause (corresponding to phase-reset). (C) PSTH of responses elicited by a short train (5 impulses @100 Hz) to 20 MF, 20 AA, and 89 PF synapses plus 20 inhibitory synapses activated 10 ms after the excitatory input. Note that the decrease of response bursts compared to B. (D) Number of spikes and pause length as a function of the number of inhibitory synapse and of the lag of inhibition with respect to excitation.