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. 2020 Dec 10;7(1):114–122. doi: 10.1021/acsinfecdis.0c00656

Figure 2.

Figure 2

Partition ratio measurements for inhibition by ETX1317 of several β-lactamases. The partition ratios were 1.1 for KPC-2, 0.7 for CTX-M-15, 1.1 for OXA-48, 1.0 for AmpC, and 0.9 for SHV-5. Incubations of enzyme and inhibitor were for 3 h with KPC-2 and 1 h with the other enzymes.