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. 2021 Jan 22;15:213–225. doi: 10.2147/OPTH.S279001

Table 3.

Adverse Events and Secondary Surgical Interventions (Safety Analysis Set)

First Eye (n = 73) Second Eye (n = 68)
Preferred term n (%) E n (%) E
 Posterior capsule opacification 4a (5.5) 4 2a (2.9) 2
 Macular fibrosis 3 (4.1) 3 1 (1.5) 1
 Punctate keratitis 1 (1.4) 2 0 0
 Glare 1 (1.4) 1 1 (1.5) 1
 Macular holeb 1 (1.4) 1 0 0
 Ocular hyperemia 1 (1.4) 1 0 0
 Retinal injury 1 (1.4) 1 0 0
 Retinal pigment epitheliopathy 0 0 1 (1.5) 1
 Vision blurred 1 (1.4) 1 0 0
 Vitreous detachment 1 (1.4) 1 1 (1.5) 1
Ocular adverse device effects
 Vision blurred 1 (1.4) 1 0 0
First Eye, n (%) Second Eye, n (%)
Secondary surgical interventions 0 0
Subjective PCO or posterior capsulotomy
 None 69 (94.5) 66 (97.1)
 Clinically nonsignificant 1 (1.4) 1 (1.5)
 Clinically significant 1 (1.4) 1 (1.5)
 Clinically significant requiring Nd:YAG treatment 2 (2.7) 0
 Posterior capsulotomy 0 0

Notes: aTwo first eyes and one second eye had events described as posterior capsular plaques. bSerious adverse device effect.

Abbreviations: E, event; Nd:YAG, neodymium-doped yttrium aluminum garnet; PCO, posterior capsular opacity.