Table 3.
All-Cause and MS-Related Healthcare Costs and Utilization in the 12-Month Pre- and Post-Index Periods
| All Patients (N=5906) | Oral (n=1701) | Injectable (n=3748) | Infusion (n=457) | |||||
|---|---|---|---|---|---|---|---|---|
| Pre-Index | Post-Index | Pre-Index | Post-Index | Pre-Index | Post-Index | Pre-Index | Post-Index | |
| All-cause healthcare costs and utilization, mean (SD) | ||||||||
| Costs (USD) | ||||||||
| Total healthcare | $18,614 ($26,432) | $79,066 ($52,735) | $17,849 ($22,665) | $70,970 ($36,681) | $17,925 ($25,999) | $82,521 ($58,569) | $27,121 ($38,720) | $80,871 ($49,627) |
| Total medical | $15,227 ($22,462) | $14,097 ($27,149) | $13,913 ($18,746) | $11,935 ($22,052) | $15,203 ($22,602) | $12,142 ($23,678) | $20,310 ($31,515) | $38,180 ($49,950) |
| Inpatient visit | $3900 ($14,800) | $2767 ($15,055) | $3,292 ($11,894) | $2373 ($12,960) | $3833 ($14,562) | $2798 ($15,877) | $6710 ($23,609) | $3980 ($15,350) |
| ED visit | $1529 ($4964) | $1069 ($3417) | $1452 ($3961) | $1145 ($3544) | $1562 ($5458) | $1010 ($3338) | $1546 ($3963) | $1272 ($3571) |
| Outpatient visit | $9798 ($12,254) | $10,261 ($19,128) | $9169 ($11,000) | $8417 ($14,091) | $9808 ($12,354) | $8335 ($12,486) | $12,054 ($15,256) | $32,928 ($46,460) |
| Outpatient pharmacy | $3388 ($11,312) | $64,969 ($47,920) | $3936 ($11,205) | $59,035 ($29,332) | $2722 ($9317) | $70,378 ($54,187) | $6811 ($21,425) | $42,692 ($39,145) |
| Utilization, mean (SD) unless otherwise noted | ||||||||
| Inpatient admission, n (%) | 1070 (18.1) | 613 (10.4) | 296 (15.8) | 176 (10.3) | 694 (18.5) | 379 (10.1) | 107 (23.4) | 58 (12.7) |
| LOS | 9.5 (21.9) | 14.4 (32.5) | 9.2 (14.3) | 12.6 (20.0) | 8.9 (21.9) | 13.9 (32.2) | 14.5 (33.7) | 23.9 (55.8) |
| Patients with ED visit, n (%) | 2034 (34.4) | 1501 (25.4) | 568 (33.4) | 451 (26.5) | 1309 (34.9) | 927 (24.7) | 157 (34.4) | 123 (26.9) |
| Number of ED visits | 0.6 (1.3) | 0.5 (1.3) | 0.6 (1.1) | 0.5 (1.3) | 0.6 (1.3) | 0.5 (1.3) | 0.7 (1.6) | 0.5 (1.1) |
| MS-related healthcare costs and utilization, mean (SD) | ||||||||
| Costs (USD) | ||||||||
| Total healthcare | $9614 ($35,343) | $72,744 ($60,976) | $11,532 ($49,716) | $65,149 ($65,133) | $7836 ($26,585) | $76,197 ($60,204) | $17,060 ($32,532) | $72,703 ($47,287) |
| Total medical | $7394 ($33,750) | $10,186 ($41,386) | $8807 ($48,557) | $9894 ($58,840) | $6059 ($24,910) | $7518 ($27,890) | $13,086 ($28,412) | $33,162 ($47,882) |
| Inpatient visit | $1550 ($7793) | $714 ($6251) | $1,321 ($5945) | $691 ($6580) | $1353 ($5917) | $714 ($6,175) | $4012 ($18,982) | $798 ($5587) |
| ED visit | $428 ($1941) | $663 ($2680) | $473 ($1911) | $724 ($2803) | $368 ($1860) | $625 ($2599) | $744 ($2570) | $747 ($2861) |
| Outpatient visit | $5417 ($32,287) | $8809 ($40,099) | $7013 ($47,917) | $8479 ($57,816) | $4338 ($23,741) | $6178 ($26,107) | $8330 ($16,753) | $31,617 ($46,699) |
| Outpatient pharmacy | $2220 ($9047) |
$62,558 ($47,519) | $2725 ($9170) |
$55,255 ($29,163) | $1777 ($7766) |
$68,679 ($53,603) | $3974 ($15,660) |
$39,541 ($37,722) |
| Utilization, mean (SD) unless otherwise noted | ||||||||
| Inpatient admission, n (%) | 509 (8.6) | 194 (3.3) | 127 (7.5) | 54 (3.2) | 321 (8.6) | 122 (3.3) | 61 (13.3) | 18 (3.9) |
| LOS | 6.7 (14.6) | 11.9 (34.2) | 6.0 (8.7) | 8.0 (9.7) | 5.7 (13.4) | 10.1 (25.1) | 13.7 (25.2) | 35.2 (88.7) |
| Patients with ED visit, n (%) | 765 (13.0) | 962 (16.3) | 246 (14.5) | 301 (17.7) | 427 (11.4) | 583 (15.6) | 92 (20.1) | 78 (17.1) |
| Number of ED visits | 0.2 (0.8) | 0.3 (1.0) | 0.2 (0.7) | 0.3 (1.0) | 0.2 (0.7) | 0.3 (1.0) | 0.4 (1.2) | 0.3 (0.8) |
Abbreviations: ED, emergency department; LOS, length of stay; MS, multiple sclerosis.