Table 4.
Multivariate Analysis of Post-Index Outcomes
| Variables | Category | Odds Ratio (95% Confidence Interval) | P Value |
|---|---|---|---|
| Logistic regression model for adherence | |||
| Index DMT* | Infusion | 1.15 (0.94–1.41) | 0.1634 |
| Oral | 1.03 (0.90–1.17) | 0.6637 | |
| Logistic regression model for persistence | |||
| Index DMT* | Infusion | 1.19 (0.97–1.46) | 0.1008 |
| Oral | 1.07 (0.94–1.22) | 0.3017 | |
| Logistic regression model for relapse | |||
| Index DMT* | Infusion | 0.80 (0.60–1.06) | 0.1233 |
| Oral | 1.03 (0.86–1.23) | 0.7481 | |
| Gamma model with log link for all-cause healthcare costs | |||
| Index DMT* | Infusion | 1.00 (0.95–1.06) | 0.8732 |
| Oral | 0.95 (0.91–0.98) | 0.0040 | |
| Gamma model with log link for MS-related healthcare costs | |||
| Index DMT* | Infusion | 1.00 (0.94–1.07) | 0.8808 |
| Oral | 0.92 (0.89–0.96) | 0.0001 | |
Note: *Reference, injectable.
Abbreviations: DMT, disease-modifying therapy; MS, multiple sclerosis.