Table 3.

Multivariate Analysis to Identify Independent Risk Factors Associated with Local Anesthetic Hypersensitivity in All Patients Referred to Our Allergy Clinic for Assessment (n = 398)

Variables	Relative Risk (95% CI)	p
Personal history of DHR with NSAID	0.888 (0.246–3.202)	0.856
Personal history of DHR with antibiotics	0.404 (0.087–1.887)	0.249
Personal history of DHR with LA	4.007 (1.115–14.397)	0.033

Abbreviations: CI, confidence interval; CU, chronic urticaria; DHR, drug hypersensitivity reaction; LA, local anesthetic; NSAID, nonsteroidal anti-inflammatory drugs.