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. 2021 Jan 25;5(1):011501. doi: 10.1063/5.0029860

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© 2021 Author(s).

2473-2877/2021/5(1)/011501/11

All article content, except where otherwise noted, is licensed under a Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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FIG. 5. — (a) Structural design of Cilengitide-loaded Pep-1-conjugated liposomes. (b) Confocal micrographs of human glioma cells treated with liposomes before (left) and after (right) Pep-1 conjugation. Coumarin-6 (green) was used as a tracking agent. Scale bar = 20 μm. (c) Ki67 immunohistochemical analysis of sectioned tumors from mice. Control-untreated; blank NL-blank liposome; CLG-free cilengitide; CNL-cilengitide loaded liposome; and PeCNL-Pep-1-conjugated cilengitide-loaded liposome. Reprinted with permission from Jiao et al., “Pep-1 peptide-functionalized liposome to enhance the anticancer efficacy of cilengitide in glioma treatment,” Colloids Surf., B 158, 68–75 (2017). Copyright 2017 Elsevier.