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Emodin inhibited glycolysis in renal cancer cells in vitro. (a) Emodin induced significant reduction of glucose-6-phosphate in OS-RC-2 and 786-O renal cancer cells in a dose-dependent manner. (b) Pyruvate was decreased markedly by Emodin in OS-RC-2 and 786-O cells in dose-dependent manner. (c) The reduction of ATP induced by Emodin was dependent on the drug concentration.
