Table 4.

Answers refer to target Ig level, monitor, and stop of Ig replacement.

Question	Answers	N (%)
Do you routinely start Ig replacement for patients with isolated low serum IgG level who do not have a history of recurrent or severe infection?	No	31 (64.58)
	Yes, if IgG below lower limit of reference	13 (27.08)
	Yes, only if total IgG < 4 g/L	2 (4.17)
	Yes, in selected patients	2 (4.17)
Do you use intravenous Ig replacement?	No, I do not use IVIG	21 (43.75)
	Yes	27 (56.25)
Do you use subcutaneous Ig replacement?	No, I do not use SCIg	44 (91.67)
	Yes	4 (8.33)
Do you monitor IgG levels during Ig replacement, and if so, how often?	No	11 (22.92)
	Opportunistically (e.g., only if infections arise)	16 (33.33)
	Every month (or more frequently)	10 (20.83)
	Every 2–6 months	6 (12.50)
	Annually	0 (0)
	I don’t know	2 (4.17)
	Other	3 (6.25)
What serum Ig level do you aim for, for IV Ig replacement?	I don’t know	9 (18.70)
	Lower than 6 g/L	6 (12.50)
	6–15 g/L	9 (18.70)
	Higher than 15 g/L	16 (33.30)
	Within normal reference range	8 (16.70)
Do you use IgG levels to adjust the Ig replacement dose?	No	42 (87.50)
	Yes	6 (12.50)
When do you stop Ig replacement?	I do not stop Ig replacement unless adverse events occur	11 (22.92)
	After a fixed duration of treatment	30 (62.50)
	Other	10 (20.83)

Note: Ig = immunoglobulin, IVIG = intravenous immunoglobulin, SCIG = subcutaneous immunoglobulin.