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. 2021 Jan 22;100(3):e24353. doi: 10.1097/MD.0000000000024353

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Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0

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Intraoperative hemodynamic and bispectral index changes. Error bar means standard deviation. The changes in mean blood pressure (MBP, upper frame) and heart rate (HR, middle frame) were significantly different between the control (●, filled circle) and dexmedetomidine (□, empty square) groups. MBP and HR were significantly lower in the dex group than in the control group. Changes in bispectral index were not significantly different between the 2 groups. There are 6 time points of measurement: Baseline, before anesthesia induction; IND10, 10 min after anesthesia induction (at the end of study drug infusion); PP10 and PP30, at 10 min and 30 min after pneumoperitoneum; Op End, at the completion of surgery; extubation, immediately after extubation. ^∗P < .05, versus baseline value within the group.