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. 2021 Jan 22;100(3):e24058. doi: 10.1097/MD.0000000000024058

Table 2.

Performance analysis of different cutoff values of fecal calprotectin in relation to endoscopic and histological criteria.

Criteria Cutoff (μg/g) Sensitivity Specificity PPV NPV Accuracy
Endoscopic 400 44.4 (27.6–62.7) 73.6 (60.4–83.6) 46.2 (28.8–64.5) 72.2 (59.1–82.4) 63.8 (52.8-73.4)
200 66.7 (47.8–81.4) 66.0 (52.6–77.3) 50.0 (34.5–65.6) 79.6 (65.5–88.9) 66.2 (55.4-75.7)
100 81.5 (63.3–91.8) 54.7 (41.4–67.3) 47.8 (34.1–61.7) 85.3 (69.9–93.6) 63.8 (52.8-73.4)
Histological 400 66.7 (46.7–82.0) 82.1 (70.2–90.0) 61.5 (42.5–77.6) 85.2 (73.4–92.3) 77.5 (67.2-85.3)
200 79.2 (59.5–90.8) 69.6 (56.7–80.1) 52.8 (37.0–68.0) 88.6 (76.0–95.0) 72.5 (61.9-81.1)
100 91.7 (74.1–97.7) 57.1 (44.1–69.2) 47.8 (34.1–61.9) 94.1 (80.9–98.4) 63.8 (52.8-73.4)
Deep remission (combined endoscopic-histological) 400 50.0 (34.1–65.9) 80.4 (66.8–89.4) 65.4 (46.2–80.6) 68.5 (55.3–79.3) 67.5 (56.6-76.8)
200 67.6 (50.8–80.8) 71.7 (57.4–82.7) 63.9 (47.6–77.5) 75.0 (60.6–85.4) 70.0 (59.2-78.9)
100 82.4 (66.5–91.6) 60.9 (46.5–73.6) 60.9 (46.5–73.6) 82.4 (66.5–91.6) 70.0 (59.2-78.9)