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. 2021 Jan 22;100(3):e24103. doi: 10.1097/MD.0000000000024103

Table 3.

Subgroup analyses of the effect of salviae miltiorrhizae and ligustrazine hydrochloride injection for improving peroneal nerve MCV and SCV.

Subgroup Median nerve MCV Median nerve SCV
Studies Patient MD (95% CI) Studies Patient MD (95CI)
Dose
 Intravenous infusion 20 ml 2[23,27] 146 3.11 (1.97–4.25) 2[23,27] 146 4.73 (2.33–7.14)
 Intravenous infusion 15ml 2[25,32] 160 9.00 (7.28–10.72) 2[25,32] 160 7.21 (5.89–8.54)
 Intravenous infusion 10ml 6[24,2931,3536] 597 4.86 (3.77–5.96) 6[24,2931,3536] 597 4.49 (2.97–6.01)
 Acupoint injection 1ml 2[28,37] 160 4.80 (3.05–6.54) 2[28,37] 160 3.95 (2.38 –5.53)
Test for subgroup differences: p < 0.001, I2 = 90.4% Test for subgroup differences: P = 0.007, I2 = 75.2%
Treatment duration
 2 weeks 6[2325,29,32,34,35] 519 6.61 (4.52–8.70) 6[2325,29,32,34,35] 519 6.23 (5.27–7.18)
 3 weeks 3[27,31,36] 284 3.88 (2.56–5.21) 3[27,31,36] 284 4.46 (3.16–5.76)
 4 weeks 1[30] 100 3.70 (1.90–5.50) 1[30] 100 1.90 (0.29–3.51)
 8 weeks 2[28,37] 160 4.80 (3.05–6.54) 2[28,37] 160 3.95 (2.38–5.53)
Test for subgroup differences: p = 0.13, I2 = 46.6% Test for subgroup differences: P < 0.001, I2 = 86.6%
Manufactor
 Guizhou Baite 6[23,25,3032,35] 603 5.95 (3.88–8.03) 6[23,25,3032,35] 603 4.97 (3.14–6.80)
 Jilin Sichang 2[28,36] 190 4.95 (3.40–6.50) 2[28,36] 190 3.77 (2.43–5.11)
 Other 4[24,27,29,37] 270 4.70 (2.38–7.02) 4[24,27,29,37] 270 5.36 (4.42–6.31)
Test for subgroup differences: p = 0.68, I2 = 0% Test for subgroup differences: P = 0.16, I2 = 45.3%