Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Effect of Sirt6 knockdown on APAP-induced hepatocytes damage and oxidative stress injury in vitro. AML12 cells were transfected with Sirt6 siRNA for 24 h and further treated with APAP for 24 h: (A) LDH levels, (B) and (C) ROS levels, (D) GSH levels, and (E) SOD levels were measured respectively. Data are expressed as the mean ± SD, n = 5. *P < 0.05, **P < 0.01, ***P < 0.001 versus the untreated group; #P < 0.05, ###P < 0.001 versus the control siRNA group.
