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Schematic of the mechanism underlying the YD inhibition of hepatic fibrosis development. YD could decrease miR-155 expression, which is responsible for the upregulation of CASP12, leading to the decreased secretion of inflammatory cytokines via inactivation of NF-κB pathway, and finally inhibit the development of fibrosis. Green arrows indicate the facilitation of this process, whereas red blocks represent the inhibition of this process.
