Table 4.
IC50 of 19d against BRD4 and PARP1 compared with RVX-208 and Olaparib.
| Molecular | IC50 (μmol/L) |
|||
|---|---|---|---|---|
| BRD4 | PARP1 | BRD4(BD1) | BRD4(BD2) | |
| Rvx-208 | 12.7 | – | 1.387 | 0.053 |
| Olaparib | – | 0.0013 | – | – |
| 19d | 0.4 | 4.6 | 0.44 | 0.379 |
‒Not applicable.
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