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PK profiles of compound 19d in SD rats (n = 3).
| Parameter | Ratap.o. (10 mg/kg) |
|---|---|
| t1/2 (h) | 3.10 ± 0.12 |
| Tmax (h) | 1.58 ± 0.35 |
| MRT0−∞ (h) | 5.35 ± 0.44 |
| Cmax (ng/mL) | 26.65 ± 3.66 |
| AUC0−t (h·ng/mL) | 114.43 ± 15.81 |
| AUC0−∞ (h·ng/mL) | 144.72 ± 25.51 |
Data are present as means ± SD, n = 3.
