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. 2021 Jan 26;11:2231. doi: 10.1038/s41598-021-81819-y

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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The anti-AMH antibody B10 reduces cell viability/proliferation and induces growth inhibition in tumor cells from ovarian carcinoma ascites samples. (a) Cell viability analyzed with the MTS assay after incubation with 0.3 to 333 nM B10 for 3 days. (b) Cell growth inhibition (cell confluence measured with the Celigo Imaging System) after incubation or not (NT) with 70 nM B10 for 48 h. (c) Apoptosis induction (caspase 3/7 activity) after incubation or not with increasing concentrations of B10. Figure shows mean ± SEM of 3 replicate wells. *p < 0.05; **p < 0.01; ***p < 0.001.