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Pharmacokinetic parameters of 4DPG in Balb/c mice intravenously administered with a single dose of 5 mg/kg/body weight.
| PK parameters | Values |
|---|---|
| C initial (C0) (ng/mL) | 10165.18 |
| Half-life (t1/2) (h) | 0.653 |
| Clearance (Cl) (L/h/kg) | 0.495 |
| Volume of distribution (Vd) (L/kg) | 0.466 |
| Area under curve (AUC0-t) (ng*h/mL) | 10068.884 |
| Area under curve (AUC0-∞) (ng*h/mL) | 10104.053 |
| Mean residence time (MRT) (h) | 0.306 |
| Time point considered in t1/2 calculation | 0.5–1 h |
