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. 2021 Jan 26;11:2193. doi: 10.1038/s41598-021-81810-7

Table 2.

Comparisons of anatomical and functional variables between baseline, 1-month follow-up and 3 month follow-up after the treatment.

Baseline 1-month follow-up 3-month follow-up
Mean ± SD p value* Mean ± SD p value§ Mean ± SD p value§ p value#
BCVA, LogMAR 0.14 ± 0.09 0.232 0.135 ± 0.10 1.000 0.115 ± 0.09 0.288 0.311
IOP, mmHg 15.5 ± 2.9 0.267 14.9 ± 2.4 0.827 14.7 ± 2.4 0.300 1.000
CMT, μm 275 ± 19 0.725 276 ± 19 1.000 273 ± 26 1.000 1.000
Subfoveal ChT, μm 223 ± 110 0.730 223 ± 112 1.000 221 ± 107 1.000 1.000
Retinal thickness (treated area), μm 295 ± 26 0.238 294 ± 24 1.000 292 ± 25 0.258 0.847
ChT (treated area), μm 197 ± 88 0.450 195 ± 94 1.000 201 ± 88 1.000 0.613
ONL thickness (treated area), μm 59.30 ± 13.50 0.001 64.75 ± 12.31 0.012 67.75 ± 15.52 < 0.001 0.213
ONL thickness (control area), μm 51.61 ± 10.91 0.199 53.39 ± 12.29 0.645 53.56 ± 12.31 0.204 1.000
MS (macular area), dB 13.99 ± 4.27 0.152 13.05 ± 4.19 0.148 13.65 ± 4.70 1.000 1.000
MS (treated area), dB 12.08 ± 4.65 0.404 11.08 ± 5.06 0.538 11.45 ± 5.70 1.000 1.000
MS (control area), dB 12.01 ± 4.67 0.120 11.02 ± 4.45 0.112 11.69 ± 5.21 1.000 0.910
Fixation percentage (2°), % 42.5 ± 13.2 0.649 39.3 ± 15.1 1.000 40.5 ± 17.3 1.000 1.000
Fixation percentage (4°), % 83.2 ± 12.8 0.342 78.3 ± 15.3 0.550 80.2 ± 11.8 0.969 1.000

SD standard deviation, BCVA best-corrected visual acuity, IOP intraocular pressure, CMT central macular thickness, ChT choroidal thickness, ONL outer nuclear layer, MS retinal sensitivity.

*Analysis of Variance (ANOVA) for paired samples.

§Comparison with baseline using ANOVA for paired samples with Bonferroni post-hoc analysis.

#Comparison with 1-month follow-up using ANOVA for paired samples with Bonferroni post-hoc anaysis.