Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jan 26;11:2184. doi: 10.1038/s41598-021-81986-y

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Classification of peptide modifications across three cardiac chambers. (A) Pie chart representation of the distribution of identified peptides that were either without a modification (Non-modified), with a chemical modification (Che. modification), a post translational modification (Others, Oxidations, DeA) or with an unknown modification (Unknown). Percentage distributions are shown for each of the three heart chambers (Circular bar graphs: RA, LV, LA). (B) Frequency distributions of the occurrence of six biological modifications across the three cardiac chambers. The modifications shown are: Kynurenine, Phosphorylation, Methylation, Acetylation, Hexose/Glycosylation and Gluconoylation. Next to each frequency plot, a bar graph shows the amino acids affected by the modification in percentage. (C) Table showing the most common chemical modifications identified in the dataset and the number of peptides carrying the modifications in each of the three chambers of heart. (D) Table showing the most frequent unknown mass shifts in the dataset along with a likely explanation of them from PTM-Sticker and PTM-Shepherd. To the right of the table, a frequency plot for the mass shift explained by combination phosphorylation and oxidation is shown.