Table 4.
The results of the oligodendrocytes in the hippocampus using laser confocal scanning microscopy quantification.
| Density of the positive oligodendrocytes in the hippocampus (n= 5/group) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Olig2+ cells | Olig2+/CNPase+ cells | Olig2+/CNPase− cells | ||||||||
| CA1 | CA2-3 | DG | CA1 | CA2-3 | DG | CA1 | CA2-3 | DG | ||
| Ctrl + NaCl | Mean (per mm2) | 151.82 | 268.68 | 198.56 | 71.61 | 124.28 | 91.25 | 80.21 | 144.41 | 107.31 |
| SD | 13.11 | 45.61 | 45.11 | 4.24 | 24.08 | 17.80 | 13.85 | 30.55 | 31.06 | |
| Ctrl + FLX | Mean (per mm2) | 160.42 | 264.28 | 199.57 | 61.35 | 110.83 | 89.92 | 99.07 | 153.44 | 109.94 |
| SD | 20.22 | 21.83 | 17.10 | 5.03 | 13.36 | 15.75 | 16.28 | 19.44 | 4.74 | |
| APP/PS1 + NaCl | Mean (per mm2) | 177.53* | 316.43* | 257.37* | 48.79* | 82.10* | 68.73* | 128.73* | 234.33* | 188.64* |
| SD | 21.21 | 27.75 | 29.38 | 8.10 | 5.06 | 6.22 | 25.46 | 26.72 | 30.05 | |
| APP/PS1 + FLX | Mean (per mm2) | 152.30# | 270.88# | 217.32 | 60.58# | 113.20# | 90.66# | 91.72# | 157.68# | 126.66# |
| SD | 18.15 | 31.69 | 23.72 | 5.86 | 19.28 | 5.68 | 20.62 | 27.13 | 19.30 | |
Mean is the average density of the positive cells in the hippocampus of each group. SD is the standard deviation of the mean.
*
p < 0.05 vs. the Ctrl+NaCl group.
#
p < 0.05 vs. the APP/PS1+NaCl group.