Table 5.
The density of the newborn oligodendrocytes in the hippocampus using laser confocal scanning microscopy semiquantification.
| Density of the newborn oligodendrocytes in the hippocampus (n = 5/group) | |||||||
|---|---|---|---|---|---|---|---|
| BrdU+/Olig2+ cells | BrdU+/Olig2+/CNPase+ cells | ||||||
| CA1 | CA2-3 | DG | CA1 | CA2-3 | DG | ||
| Ctrl | Mean (per mm2) | 15.24 | 22.67 | 19.62 | 11.94 | 14.67 | 17.90 |
| + NaCl | SD | 1.16 | 2.41 | 0.58 | 0.81 | 1.56 | 0.47 |
| Ctrl | Mean (per mm2) | 15.05 | 23.19 | 19.62 | 12.26 | 18.85∧ | 15.87 |
| + FLX | SD | 1.16 | 1.52 | 0.71 | 1.81 | 1.43 | 1.45 |
| APP/PS1 | Mean (per mm2) | 14.49 | 23.06 | 21.40 | 11.64 | 11.27 | 9.73* |
| + NaCl | SD | 0.65 | 1.97 | 2.72 | 0.76 | 2.95 | 1.66 |
| APP/PS1 | Mean (per mm2) | 16.04 | 19.87 | 15.95# | 13.01 | 14.40 | 13.31# |
| + FLX | SD | 1.82 | 4.58 | 2.83 | 1.52 | 1.82 | 2.75 |
Mean is the average density of the newborn oligodendrocytes in the hippocampus of each group, SD is the standard deviation of the mean.
*
p < 0.05 for the comparison of the densities of the positive oligodendrocytes between the Ctrl + NaCl group and the APP/PS1 + NaCl group.
#
p < 0.05 for the comparison of the densities of the positive oligodendrocytes between the APP/PS1 + NaCl group and the APP/PS1 + FLX group.
∧
p < 0.05 for the comparison of the densities of the positive oligodendrocytes between the Ctrl + NaCl group and the Ctrl + NaCl group.