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. 2021 Jan 13;14:598198. doi: 10.3389/fncel.2020.598198

Table 1.

Top 30 items of GO enrichment from comparison of differential genes in acupuncture and TBI rats.

Pathway q value Gene count Enrich factor
Positive regulation of CD4-positive, alpha-beta T cell activation 0.001111 4 21.15
Positive regulation of T cell mediated immunity 0.00007437 6 19.52
Endochondral ossification 0.001957 4 18.13
Positive regulation of cytokine production involved in immune response 0.002134 4 16.92
Positive regulation of leukocyte apoptotic process 0.002298 4 15.86
T cell mediated cytotoxicity 0.001003 5 15.11
Regulation of T cell mediated immunity 0.0003899 6 13.84
Response to X-ray 0.003433 4 12.69
Positive regulation of B cell proliferation 0.003433 4 12.69
T cell mediated immunity 0.00009964 8 11.8
Regulation of immunoglobulin production 0.00208 5 11.54
Positive regulation of alpha-beta T cell activation 0.002215 5 11.33
Interleukin-2 production 0.002094 5 11.13
Positive regulation of adaptive immune response 0.001019 6 11.03
Positive regulation of leukocyte mediated cytotoxicity 0.004794 4 10.8
Positive regulation of mitotic cell cycle 0.004958 4 10.57
Positive regulation of interferon-gamma production 0.005252 4 10.36
Neuron projection membrane 0.005617 4 10.15
Positive regulation of ossification 0.005813 4 9.95
Positive regulation of cell killing 0.006537 4 9.4
Regulation of heart growth 0.006928 4 9.06
Endochondral bone morphogenesis 0.007197 4 8.91
Cardiac muscle tissue morphogenesis 0.007197 4 8.91
Positive regulation of protein secretion 0.00008556 10 8.87
Regulation of cytokine production involved in immune response 0.007532 4 8.75
Leukocyte mediated cytotoxicity 0.002263 6 8.46
Regulation of B cell proliferation 0.0088 4 8.32
Outflow tract morphogenesis 0.0088 4 8.32
Positive regulation of cytokine secretion 0.002614 6 8.1
CD4-positive, alpha-beta T cell activation 0.007303 4 8.06