TABLE 1.

Demographic and performance variables between two groups.

	CF (n = 26)	HC (n = 26)	t/χ2	P
Sex (male/female, n)*	13/13	13/13	0	1.000
Age (years)#	65.42 ± 5.15	65.38 ± 4.7	0.028	0.978
Edu (years)#	9.77 ± 3.98	10.96 ± 3.24	–1.184	0.242
BDI (scores)#	3.96 ± 1.93	4.62 ± 1.13	–1.49	0.144
MoCA (scores)#	19.31 ± 3.06	26.77 ± 0.86	–11.98	< 0.001
MQ (scores)#	77.54 ± 13.64	105.58 ± 5.32	–9.767	< 0.001
Average thickness of whole brain (mm)#	2.61 ± 0.06	2.63 ± 0.11	–1.208	0.233
Proportion of brain parenchyma#	0.73 ± 0.022	0.75 ± 0.033	–3.273	0.002
Total white fiber number#	30982.19 ± 6706.00	45014.62 ± 4539.86	–8.835	< 0.001
FI (scores)#	5.54 ± 0.76	2.19 ± 1.266	8.263	< 0.001
Grip strength (kg)#	23.03 ± 3.55	25.46 ± 3.83	–2.380	0.021
TIV (cm3)#	1332.19 ± 114.20	1386.00 ± 121.58	–1.645	0.106

Edu, education year; BDI, Beck Depression Inventory; MoCA, Montreal Cognitive Assessment; FI, frailty index; TIV, total intracranial volume; MQ, Wechsler’s Memory quotient; CF, cognitive frailty; HC, healthy control. *Chi-square test was used for data analysis. ^#t-test was used for data analysis. Value of volume was presented by mean ± standard deviation. p−values for cognitive frailty vs. healthy control group comparison.