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. 2021 Jan 26;11:2271. doi: 10.1038/s41598-021-81927-9

Table 1.

Baseline participant characteristics (stratified by PHQ-9 ≥ 10 at follow-up).

Variable All (N = 10,120) PHQ-9 ≥ 10 at FU (N = 448) PHQ-9 ≤ 9 at FU (N = 9672) p
Sociodemographic
Women (%) 46.1% (4670) 53.1% (238) 45.8% (4432) 0.003
Age 54.3 (10.9) 51.2 (10.3) 54.5 (10.9)  < 0.001
Living with partner (%) 84.5% (8547) 79.7% (357) 84.7% (8190) 0.006
Socioeconomic status 13.45 (4.39) 12.94 (4.26) 13.48 (4.39) 0.010
Inflammation
CRP ≥ 3 mg/l (%) 23.9% (2419) 28.0% (125) 23.7% (2292) 0.041
WBC (leucocytes/nl) 6.80 (5.75/8.10) 7.10 (5.80/8.66) 6.80 (5.75/8.10) 0.002
Physical health and health behavior
Diabetes (%) 7.3% (739) 8.3% (37) 7.3% (702) 0.40
CVD (%) 8.3% (836) 7.9% (35) 8.3% (801) 0.86
Cancer (%) 7.9% (800) 8.9% (40) 7.9% (760) 0.42
Obesity (%) 22.7% (2297) 24.8% (111) 22.6% (2186) 0.30
Smoker (%) 17.2% (1738) 24.3% (108) 16.9% (1630)  < 0.001
Physical activity 7260 (5174/9390) 7590 (5500/10,140) 7230 (5156/9360) 0.019
Alcohol (% > recom. limit) 28.1% (2836) 22.7% (101) 28.3% (2735) 0.01
Mental distress
Loneliness (%) 6.6% (668) 19.0% (85) 6.1% (590)  < 0.001
PHQ-9 sum at baseline 3.13 (2.31) 5.48 (2.37) 3.02 (2.25)  < 0.001

Bold values indicate statistically significant differences.

Participant characteristics are shown as mean values and standard deviations, medians with interquartile ranges (if not fulfilling normal distribution) or as percentages and absolute numbers.

CRP C-reactive protein, CVD cardiovascular disease, FU follow-up, PHQ-9 patient health questionnaire-9, WBC white blood cell count.