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(A) Immunohistochemistry was used to test the expression of IL-24 and PKR in normal brain tissues and Grades I–II, III, and IV glioma tissues. Results showed expression of IL-24 and PKR was lower in glioma tissues than in normal brain tissues. Both IL-24 and PKR were decreased with increasing glioma grade in human glioma tissues. (B) qPCR results also showed IL-24 and PKR expression levels decreased with increasing glioma grade. *Significant difference (p < 0.05).
