Table 1.
GRADE evidence profile: Quality assessment.
| Certainty assessment | Number of patients | Effect | Certainty | Importance | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Number of studies | Study design | Risk of bias | Inconsistency | Indirectness | Imprecision | Other considerations | SLN(n) | LND(n) | Relative(95% CI) | Absolute(95% CI) | ||
| Operation time | ||||||||||||
| 8 | Observational studies | Not serious | Seriousa | Not serious | Not serious | None | 959 | 2,243 | – | MD 75.37 lower (106.36 lower to 44.38 lower) |
⨁
VERY LOW |
CRITICAL |
| Blood loss | ||||||||||||
| 6 | Observational studies | Not serious | Not serious | Not serious | Not serious | None | 709 | 631 | – | MD 54.4 lower (85.36 lower to 23.45 lower) |
⨁⨁
LOW |
CRITICAL |
| P-LN positive | ||||||||||||
| 6 | Observational studies | Not serious | Not serious | Not serious | Not serious | strong associationb | 150/797 (18.8%)c | 167/1,282 (13.0%) | OR 1.91 (1.36 to 2.68) |
92 more per 1,000 (from 39 more to 156 more) |
⨁⨁⨁ MODERATE |
CRITICAL |
| PA-LN positive | ||||||||||||
| 7 | Observational studies | Not serious | Not serious | Not serious | Not serious | None | 49/977 (5.0%) | 87/1,462 (6.0%) | OR 1.09 (0.61to 1.96) |
5 fewer per 1,000 (from 21 fewer to 51 more) |
⨁⨁
LOW |
CRITICAL |
GRADE, Grading of recommendation assessment, development, and evaluation; n, number of patients; CI, Confidence interval; MD, Mean difference; RR, Risk ratio; OR, Odds ratio; HR, Hazard Ratio; aHeterogeneity = 99%; bRR>2; c[n/total n (%)].