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. 2021 Jan 13;11:601628. doi: 10.3389/fneur.2020.601628

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Copyright © 2021 Dietrich, Hecker, Nasiri, Samsam, Issberner, Kohne, Hartung and Albrecht.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Retinal degeneration after light-induced photoreceptor loss (Li-PRL). (A) Schematic image of Li-PRL and (B) image of irradiation of C57Bl/6J mouse. (C) Change of inner retinal layers (IRL) and (D) outer retinal layers (ORL) with photoreceptors (PR) of mice over 10 weeks after Li-PRL. All graphs represent the pooled mean ± SEM; n = 3 animals per group. **p < 0.01 by area under the curve compared by ANOVA with Dunnett's post hoc test compared to irradiated control. LGN = lateral geniculate nucleus.