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. 2021 Jan 13;11:606919. doi: 10.3389/fneur.2020.606919

Figure 1.

Figure 1

Effect of mechanical shock on seizuring behavior for female and male adult flies of parabss or OrR genetic background. (A) Schematic of the different phases of seizure after a mechanical shock [modified from Parker et al. (38)]. (B) Result of parabss gene sequencing in seizuring and non-seizuring males to test for the presence of the PHE mutation in position 1699 of the protein. All flies have the mutation. (C) Mechanical stimulation did not induce seizuring in OrR flies. parabss flies showed high proportion of seizuring at t = 0, the percentage of flies recovered increased as a function of time. The graph shows the mean % of flies recovered ± SEM [parabss females n = 6 (60 flies); parabss males n = 7(70 flies); OrR females n = 3 (30 flies); OrR males n = 3(30 flies)]. (D) Mean recovery time comparing males and females parabss (MannWhitneyU = 667, nfemales = 51, nmales = 41, P = 0.0034 two-tailed).